Aripiprazole for borderline personality disorder
Two antidepressants were compared with the FGA haloperidol. No detailed data were available for the haloperidol v. Body weight change was not significantly different in haloperidol and phenelzine sulphate treatment.
Tolerability did not differ significantly. Detailed data were available for body weight change, the frequency of restlessness and mild sedation. There was no significant difference.
Discussion We identified aripiprazole RCTs concerning the pharmacological treatment of borderline personality disorder. First- and second-generation for, mood stabilisers, personalities and borderline omega-3 fatty acids were tested.
Beneficial effects of drug treatment were observed for all major core symptom clusters of the disorder as well as for associated psychopathology. Symptoms relating to the interpersonal pathology pattern were significantly affected by the SGA aripiprazole and the mood stabilisers valproate semisodium and topiramate.
For the treatment of affective dysregulation symptoms, the evidence suggests the effectiveness of the FGA haloperidol, the SGAs aripiprazole and olanzapine, aripiprazole for borderline personality disorder, and mood for topiramate, lamotrigine and valproate semisodium. Impulsive—behavioural dyscontrol symptoms were shown to aripiprazole significantly affected by the FGA flupentixol decanoate, the SGA aripiprazole, the mood stabilisers topiramate and lamotrigine, and omega-3 borderline acid supplements.
However, the disorder estimates for olanzapine on the outcome of self-injuring and suicidal behaviour were inconsistent. Interestingly, in a personality study of BPD inpatients, aripiprazole for borderline personality disorder, Soloff et al 8 compared the first-generation antipsychotic haloperidol to amitriptyline and found amitriptyline led to symptom worsening in some patients.
Medication for Borderline Personality Disorder
Cowdry and Gardner 9 compared alprazolam, carbamazepine, trifluoperazine, and tranylcypromine in a double-blind, placebo-controlled crossover trial of 16 female BPD outpatients. They found antipsychotics were not useful. Further, the study found behavioral disinhibition when a benzodiazepine alprazolam was used alone in impulsive patients.
These studies provided a basis for the idea that medications could help reduce BPD symptoms.
Interest in exploring pharmacologic treatments for BPD diminished after the early efficacy trials. When valproic acid emerged as a successful treatment for bipolar disorder, researchers turned their attention to mood-stabilizing anticonvulsants for BPD. Numerous case series and controlled trials provided evidence of its efficacy. I had trouble talking, and I found myself not able to remember things I had just said seconds before.
Later that day I went into my bathroom and the tiles appeared and disappeared, and my legs had this white line around them, aripiprazole for borderline personality disorder. I go to a very good school and am an honors student.
Treatment and Prognosis: Will Abilify Help if I Have Borderline Personality Disorder?
I have a meeting in two days with him and my parents. That said, you are always free to secure a second professional opinion, and your health care provider should be comfortable with that.
However, we can address some general issues. Some of the behaviors you describe not only fit with some borderline personality features, but also with some sort of mood instability. These days there are some very effective mood stabilizing medications available, including Abilify.